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Lowering Blood Sugar Without Weight Loss | Dr Nicola Guess

Aug 17, 2026 · 1h 9m

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About this episode

Can you meaningfully improve type 2 diabetes without losing weight? Dr Nicola Guess, registered dietitian and Senior Research Fellow at the University of Oxford, says the evidence is clear: a higher-protein, lower-carbohydrate diet can lower post-meal glucose by more than medication, no weight loss required. We also tackle the noisier end of the blood sugar conversation: glucose spikes, fruit fear, insulin-first theories of obesity, and the panic about GLP-1s and muscle loss. What We Cover: Why glucose only causes direct harm at diabetic levels How protein wakes up "sleepy" beta cells What overfeeding trials reveal about insulin and obesity Fruit, fibre, and fat quality: what matters and…