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Extend Podcast with Darshan Shah, MD

Extend Podcast with Darshan Shah, MD

178. Dr. Matt Kaeberlein: The Science, Risk, and Hype Behind Today's Longevity Trends

Jul 2, 2026 · 1h 14m

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About this episode

If you care about longevity, you have probably seen the same pattern over and over again. A new peptide, supplement, biological age test, off-label drug, or protocol starts gaining attention, and suddenly it sounds like the missing piece everyone should be using. The hard part is not wanting to be proactive. The hard part is knowing which claims have real evidence behind them, which ones are still early signals, and which ones may carry risks no one is measuring carefully enough. In this episode, I sit down with Dr. Matt Kaeberlein to talk about how to think about longevity when the answer is rarely a simple yes or no. This conversation helps separate excitement from certainty, and shows…