Can Creatine Protect the Brain from Sleep Deprivation? | HOMe Podcast #024

On this episode

About this episode

In this episode of the Health Optimization Medicine Podcast, Dr. Scott Sherr, Dr. Ted Achacoso, Dr. Allen Bookatz, and Dr. Jup Kuipers explore how acute sleep deprivation affects brain energy metabolism and whether creatine monohydrate can help preserve cognitive function when sleep loss is unavoidable. Rather than relying on stimulants like caffeine or modafinil to push through fatigue, the team examines whether directly supporting the brain's phosphocreatine and ATP systems can maintain cellular energy and cognitive performance during acute sleep deprivation. The discussion looks at recent research on single-dose creatine, brain bioenergetics, blood-brain barrier transport, clinical…