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The a16z Show

The a16z Show

Martin Shkreli on AI, Pharma, and What Actually Matters

Apr 23, 2026 · 49m

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On this episode

About this episode

Erik Torenberg speaks with Martin Shkreli, American investor and businessman, about how he sees the AI landscape, from OpenAI to Anthropic, and what actually matters beyond the hype. They also talk through the future of computing, the limits of “vibe coding,” and why biotech and pharma remain some of the toughest industries to get right.