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Mick Unplugged

Mick Unplugged

Matt Iseman: Reveals His Journey from Doctor to Comedian to Ninja Warrior Host

Aug 21, 2025 · 37m

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On this episode

About this episode

Matt Iseman is an Emmy-winning comedian, TV host, and medical doctor best known as the beloved host of American Ninja Warrior. A cancer survivor and rheumatoid arthritis warrior, Matt uses both his medical background and comedic chops to inspire resilience and hope in others. He’s a passionate advocate for the Arthritis Foundation, raising awareness and funds as a public voice for those impacted by chronic illness. Matt’s dynamic career spans stand-up comedy, television, and philanthropy, making him a true champion for transformation and relentless growth. Takeaways: Community is Healing: Matt credits finding connection with others experiencing rheumatoid arthritis as a crucial turning…