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Danny Jones Best of

Danny Jones Best of

They Won't Know What Ozempic Does for Another 10 Years | Dr. Alexis Cowan

Sep 20, 2026 · 1h 3m

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About this episode

Danny can name twenty-five people in his own life who are on a GLP-1. Alexis Cowan thinks we are going to be horrified by what their health looks like in a couple of decades, and her argument has nothing to do with willpower or calories. These drugs trick the body into believing energy is abundant, so appetite shuts down and energy expenditure climbs at the exact moment the body is actually running a deficit. What gets burned is not only fat. It is bone, muscle, tendon, and, she suspects, the mitochondria that produce your energy in the first place. She also repeats a blunter version she has heard from another researcher: these things are taking decades off people's lives. 00:00 Ozempic and…