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Great Company with Jamie Laing

Great Company with Jamie Laing

DR FEDERICA AMATI: How Weight Loss Drugs Can Rewire Your Brain

Sep 8, 2026 · 1h 21m

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About this episode

Dr Federica Amati is the Head Nutritionist at ZOE and author of The Appetite Reset, https://amzn.eu/d/0iodLEof. She first came on the show back in 2024 and she completely blew my mind. Now she's back…And this time, she's tackling weight loss drugs. What started as a prescription treatment for diabetes has become a global cultural phenomenon, with millions now taking GLP-1s to lose weight. Dr Federica reveals that people can eat up to 40% less food while taking these drugs, causing significant changes to their bodies. She also explains how they can rewire our brains, as well as the short and long term effects of taking them. In this episode, she shares: How weight loss drugs really affect…