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The Dr. Josh Axe Show

The Dr. Josh Axe Show

Harvard Doctor reveals #1 Cause of Aging You've Never Heard Of | Dr. Andrew Salzman

Jun 25, 2026 · 1h 1m

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About this episode

In this episode of The Dr. Josh Axe Show, Dr. Josh Axe sits down with Dr. Andrew Salzman, a Harvard-trained ICU physician and pioneering researcher in NAD, cellular energy, leaky gut, and longevity science, to uncover one of the most important shifts in how we understand aging: your body may not simply be “wearing out” — it may be losing the energy and repair capacity it needs to rebuild itself. Dr. Salzman explains why NAD+ is central to mitochondrial function, ATP production, DNA repair, antioxidant defense, and healthy aging. He breaks down how chronic inflammation, leaky gut, PARP activation, and CD38 can drain NAD levels, leaving cells unable to efficiently produce energy or repair…